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Furthermore, the administration of the dietary supplement did not result in any changes in the total cholesterol in the patients evaluated’. Women who were given capsules made up of 2 grams of a combination of gamma linolenic acid, oleic acid, linoleic acid, other polyunsaturated acids and supplement E reported considerably eased PMS symptoms at both 3 and 6 months after they started the treatment. Speaking about the full total results, Rocha Filho stated, ‘The negative effect of PMS on a woman’s routine activities and standard of living may be significant, in addition to the repercussions on financial costs resulting predominantly from a reduction in productivity.