Sahni’s research group first started investigating the rickettsia bacterias as a model to review the biological adjustments that happen in the lining of the blood vessels as the bacteria travels through the blood stream. Initially they were looking at what forms of cellular adjustments occur in response to the disease. They found that cells go through oxidative stress and produce harmful free of charge radicals, causing inflammation and other complications. Researchers hypothesized that antioxidants might serve as useful therapies after examining the harm to infected cells, as noticed by electron microscopy, and through biochemical evidence proving oxidative stress , a term used to describe a known level of damage in cells, tissue and organs.Related StoriesLiposomal sizing and the Coulter basic principle: an interview with Professor Melvin E. Although it is well established in boxers, recently, CTE has been proven to exist in various other athletes, including collegiate and professional football players and a specialist hockey player. CTE was initially reported in the medical literature in 1928, and the conditions Traumatic CTE and Encephalopathy were first used in the 1960s. The disease is characterized by the build-up of a toxic proteins called tau in the form of neurofibrillary tangles and neuropil threads through the entire brain.